Publications by RCLR members (2018)

Akbari-Alavijeh, S., Soleimanian-Zad, S., Sheikh-Zeinoddin, M., and Hashmi, S. (2018) Pistachio hull water-soluble polysaccharides as a novel prebiotic agent. Int. J. Biol. Macromol. 107, 808-816

Al-Anazi, A., Parhar, R., Saleh, S., Al-Hijailan, R., Inglis, A., Al-Jufan, M., Bazzi, M., Hashmi, S., Conca, W., Collison, K., and Al-Mohanna, F. (2018) Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression. Data Brief. 21, 2395-2397

Al-Anazi, A., Parhar, R., Saleh, S., Al-Hijailan, R., Inglis, A., Al-Jufan, M., Bazzi, M., Hashmi, S., Conca, W., Collison, K., and Al-Mohanna, F. (2018) Intracellular calcium and NF-kB regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes. Life Sci. 212, 275-284

Beavers, K. M., Walkup, M. P., Weaver, A. A., Lenchik, L., Kritchevsky, S. B., Nicklas, B. J., Ambrosius, W. T., Stitzel, J. D., Register, T. C., Shapses, S. A., Marsh, A. P., and Rejeski, W. J. (2018) Effect of Exercise Modality During Weight Loss on Bone Health in Older Adults With Obesity and Cardiovascular Disease or Metabolic Syndrome: A Randomized Controlled Trial. J. Bone Miner. Res. 33, 2140-2149

Bircsak, K. M., Moscovitz, J. E., Wen, X., Archer, F., Yuen, P. Y. S., Mohammed, M., Memon, N., Weinberger, B. I., Saba, L. M., Vetrano, A. M., and Aleksunes, L. M. (2018) Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas. Drug Metab Dispos. 46, 619-627

Blundell, C., Yi, Y. S., Ma, L., Tess, E. R., Farrell, M. J., Georgescu, A., Aleksunes, L. M., and Huh, D. (2018) Placental Drug Transport-on-a-Chip: A Microengineered In Vitro Model of Transporter-Mediated Drug Efflux in the Human Placental Barrier. Adv. Healthc. Mater. 7,

Brey, C. W., kbari-Alavijeh, S., Ling, J., Sheagley, J., Shaikh, B., Al-Mohanna, F., Wang, Y., Gaugler, R., and Hashmi, S. (2018) Salts and energy balance: A special role for dietary salts in metabolic syndrome. Clin. Nutr.

Byun, S., Kim, D. H., Ryerson, D., Kim, Y. C., Sun, H., Kong, B., Yau, P., Guo, G., Xu, H. E., Kemper, B., and Kemper, J. K. (2018) Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis. Nat. Commun. 9, 2590

Carman, G. M. and Han, G. S. (2018) Phosphatidate phosphatase regulates membrane phospholipid synthesis via phosphatidylserine synthase. Adv. Biol. Regul. 67, 49-58

Cheng, K., Metry, M., Felton, J., Shang, A. C., Drachenberg, C. B., Xu, S., Zhan, M., Schumacher, J., Guo, G. L., Polli, J. E., and Raufman, J. P. (2018) Diminished gallbladder filling, increased fecal bile acids, and promotion of colon epithelial cell proliferation and neoplasia in fibroblast growth factor 15-deficient mice. Oncotarget. 9, 25572-25585

Feng, S., Dai, Z., Liu, A. B., Huang, J., Narsipur, N., Guo, G., Kong, B., Reuhl, K., Lu, W., Luo, Z., and Yang, C. S. (2018) Intake of stigmasterol and beta-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1863, 1274-1284

Gallo-Ebert, C., Francisco, J., Liu, H. Y., Draper, R., Modi, K., Hayward, M. D., Jones, B. K., Buiakova, O., McDonough, V., and Nickels, J. T., Jr. (2018) Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease. J. Biol. Chem. 293, 5956-5974

Garretto, D., Kim, Y. K., Quadro, L., Rhodas, R. R., Pimentel, V., Crnosija, N. A., Nie, L., Bernstein, P., Tropper, P., and Neal-Perry, G. S. (2018) Vitamin A and beta-carotene in pregnant and breastfeeding post-bariatric women in an urban population. J. Perinat. Med.

Gast, C., Marinaki, A., renas-Hernandez, M., Campbell, S., Seaby, E. G., Pengelly, R. J., Gale, D. P., Connor, T. M., Bunyan, D. J., Hodanova, K., Zivna, M., Kmoch, S., Ennis, S., and Venkat-Raman, G. (2018) Autosomal dominant tubulointerstitial kidney disease-UMOD is the most frequent non polycystic genetic kidney disease. BMC. Nephrol. 19, 301

George, B., Joy, M. S., and Aleksunes, L. M. (2018) Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy. Exp. Biol. Med. (Maywood. ) 243, 272-282

Giordano, E. and Quadro, L. (2018) Lutein, zeaxanthin and mammalian development: Metabolism, functions and implications for health. Arch. Biochem. Biophys. 647, 33-40

Grissom, L. E., Harty, M. P., Guo, G. W., and Kecskemethy, H. H. (2018) Maturation of pelvic ossification centers on computed tomography in normal children. Pediatr. Radiol. 48, 1902-1914

Guo, G. L. and Xie, W. (2018) Metformin action through the microbiome and bile acids. Nat. Med. 24, 1789-1790

Hardman, D., Ukey, R., and Fakas, S. (2018) Phosphatidate phosphatase activity is induced during lipogenesis in the oleaginous yeast Yarrowia lipolytica. Yeast 35, 619-625

Harrison, E. H. and Quadro, L. (2018) Apocarotenoids: Emerging Roles in Mammals. Annu. Rev. Nutr. 38, 153-172

Ibrahim, M. E., Chang, C., Hu, Y., Hogan, S. L., Mercke, N., Gomez, M., O'Bryant, C. L., Bowles, D. W., George, B., Wen, X., Buckley, B., Aleksunes, L., and Joy, M. S. (2018) Pharmacokinetic determinants of cisplatin-induced subclinical kidney injury in oncology patients. Eur. J. Clin. Pharmacol.

Imbert, L., Gourion-Arsiquaud, S., Villarreal-Ramirez, E., Spevak, L., Taleb, H., van der Meulen, M. C. H., Mendelsohn, R., and Boskey, A. L. (2018) Dynamic structure and composition of bone investigated by nanoscale infrared spectroscopy. PLoS. One. 13, e0202833

Joseph, L. B., Composto, G. M., Perez, R. M., Kim, H. D., Casillas, R. P., Heindel, N. D., Young, S. C., Lacey, C. J., Saxena, J., Guillon, C. D., Croutch, C. R., Laskin, J. D., and Heck, D. E. (2018) Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug. Toxicol. Lett. 293, 77-81

Kim, Y. C., Byun, S., Seok, S., Guo, G., Xu, H. E., Kemper, B., and Kemper, J. K. (2018) Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption. Gastroenterology

Kim, Y. C., Seok, S., Byun, S., Kong, B., Zhang, Y., Guo, G., Xie, W., Ma, J., Kemper, B., and Kemper, J. K. (2018) AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. Nat. Commun. 9, 540

Komakula, S. S. B., Tumova, J., Kumaraswamy, D., Burchat, N., Vartanian, V., Ye, H., Dobrzyn, A., Lloyd, R. S., and Sampath, H. (2018) The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue. Sci. Rep. 8, 14886
Kong, B. and Guo, G. L. (2018) Is This the Time to Reconsider the Names for Xenobiotic Nuclear Receptors? Hepatology

Kong, B., Sun, R., Huang, M., Chow, M. D., Zhong, X. B., Xie, W., Lee, Y. H., and Guo, G. L. (2018) Fibroblast Growth Factor 15-Dependent and Bile Acid-Independent Promotion of Liver Regeneration in Mice. Hepatology 68, 1961-1976

Kramer, C. K., Ye, C., Campbell, S., and Retnakaran, R. (2018) Comparison of New Glucose-Lowering Drugs on Risk of Heart Failure in Type 2 Diabetes: A Network Meta-Analysis. JACC. Heart Fail. 6, 823-830

Krumm, E. A., Patel, V. J., Tillery, T. S., Yasrebi, A., Shen, J., Guo, G. L., Marco, S. M., Buckley, B. T., and Roepke, T. A. (2018) Organophosphate Flame-Retardants Alter Adult Mouse Homeostasis and Gene Expression in a Sex-Dependent Manner Potentially Through Interactions With ERalpha. Toxicol. Sci. 162, 212-224

Liu, X., Guo, G. L., Kong, B., Hilburn, D. B., Hubchak, S. C., Park, S., LeCuyer, B., Hsieh, A., Wang, L., Fang, D., and Green, R. M. (2018) Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice. Hepatology 68, 304-316

Marti, G. E., Hutson, R. B., Goban, A., Campbell, S. L., Poli, N., and Ye, J. (2018) Imaging Optical Frequencies with 100 muHz Precision and 1.1 mum Resolution. Phys. Rev. Lett. 120, 103201

Meers, P. R., Liu, C., Chen, R., Bartos, W., Davis, J., Dziedzic, N., Orciuolo, J., Kutyla, S., Pozo, M. J., Mithrananda, D., Panzera, D., and Wang, S. (2018) Vesicular Delivery of the Antifungal Antibiotics of Lysobacter enzymogenes C3. Appl. Environ. Microbiol. 84,

Memon, N., Griffin, I. J., Lee, C. W., Herdt, A., Weinberger, B. I., Hegyi, T., Carayannopoulos, M. O., Aleksunes, L. M., and Guo, G. L. (2018) Developmental regulation of the gut-liver (FGF19-CYP7A1) axis in neonates. J. Matern. Fetal Neonatal Med. 1-6

Moretti, A., Li, Q., Chmielowski, R., Joseph, L. B., Moghe, P. V., and Uhrich, K. E. (2018) Nanotherapeutics Containing Lithocholic Acid-Based Amphiphilic Scorpion-Like Macromolecules Reduce In Vitro Inflammation in Macrophages: Implications for Atherosclerosis. Nanomaterials. (Basel) 8,

Neinast, M. D., Jang, C., Hui, S., Murashige, D. S., Chu, Q., Morscher, R. J., Li, X., Zhan, L., White, E., Anthony, T. G., Rabinowitz, J. D., and Arany, Z. (2018) Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Cell Metab

Nikonorova, I. A., Mirek, E. T., Signore, C. C., Goudie, M. P., Wek, R. C., and Anthony, T. G. (2018) Time-resolved analysis of amino acid stress identifies eIF2 phosphorylation as necessary to inhibit mTORC1 activity in liver. J. Biol. Chem. 293, 5005-5015

Pappas, A., Kendall, A. C., Brownbridge, L. C., Batchvarova, N., and Nicolaou, A. (2018) Seasonal changes in epidermal ceramides are linked to impaired barrier function in acne patients. Exp. Dermatol. 27, 833-836

Rice, C. A., Campbell, S. J., Bisson, C., Owen, H. J., Sedelnikova, S. E., Baker, P. J., Rice, D. W., Henriquez, F. L., and Roberts, C. W. (2018) Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials. PLoS. One. 13, e0198827

Rooney, J., Oshida, K., Vasani, N., Vallanat, B., Ryan, N., Chorley, B. N., Wang, X., Bell, D. A., Wu, K. C., Aleksunes, L. M., Klaassen, C. D., Kensler, T. W., and Corton, J. C. (2018) Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor. PLoS. One. 13, e0200004

Shams-White, M. M., Chung, M., Fu, Z., Insogna, K. L., Karlsen, M. C., LeBoff, M. S., Shapses, S. A., Sackey, J., Shi, J., Wallace, T. C., and Weaver, C. M. (2018) Animal versus plant protein and adult bone health: A systematic review and meta-analysis from the National Osteoporosis Foundation.  PLoS. One. 13, e0192459
Shapses, S. (2018) Osteoporosis. Ann. Intern. Med. 168, 306

Spiegler, E., Kim, Y. K., Hoyos, B., Narayanasamy, S., Jiang, H., Savio, N., Curley, R. W., Jr., Harrison, E. H., Hammerling, U., and Quadro, L. (2018) b-apo-10'-carotenoids support normal embryonic development during vitamin A deficiency. Sci. Rep. 8, 8834

Su, W. M., Han, G. S., Dey, P., and Carman, G. M. (2018) Protein kinase A phosphorylates the Nem1-Spo7 protein phosphatase complex that regulates the phosphorylation state of the phosphatidate phosphatase Pah1 in yeast. J. Biol. Chem. 293, 15801-15814

Szilagyi, J. T., Fussell, K. C., Wang, Y., Jan, Y. H., Mishin, V., Richardson, J. R., Heck, D. E., Yang, S., Aleksunes, L. M., Laskin, D. L., and Laskin, J. D. (2018) Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase. Toxicol. Appl. Pharmacol. 359, 102-107

Szilagyi, J. T., Gorczyca, L., Brinker, A., Buckley, B., Laskin, J. D., and Aleksunes, L. M. (2018) Placental BCRP/ABCG2 transporter prevents fetal exposure to the estrogenic mycotoxin zearalenone. Toxicol. Sci.

Toledo, A., Huang, Z., Coleman, J. L., London, E., and Benach, J. L. (2018) Lipid rafts can form in the inner and outer membranes of Borrelia burgdorferi and have different properties and associated proteins. Mol. Microbiol. 108, 63-76

Tuazon, M. A., Campbell, S. C., Klein, D. J., Shapses, S. A., Anacker, K. R., Anthony, T. G., Uzumcu, M., and Henderson, G. C. (2018) Effects of ovariectomy and exercise training intensity on energy substrate and hepatic lipid metabolism, and spontaneous physical activity in mice. Metabolism 83, 234-244

Wang, P., Sachar, M., Guo, G. L., Shehu, A. I., Lu, J., Zhong, X. B., and Ma, X. (2018) Liver metabolomics in a mouse model of erythropoietic protoporphyria. Biochem. Pharmacol. 154, 474-481

Wang, Y., Buckendahl, P., Sharma, K., Miller, J. W., and Shapses, S. A. (2018) Expression of vitamin D hydroxylases and bone quality in obese mice consuming saturated or monounsaturated enriched high-fat diets. Nutr. Res. 60, 106-115

Zhang, J., Liu, J., Norris, A., Grant, B. D., and Wang, X. (2018) A novel requirement for ubiquitin-conjugating enzyme UBC-13 in retrograde recycling of MIG-14/Wntless and Wnt signaling. Mol. Biol. Cell 29, 2098-2112

Zhang, M., Kong, B., Huang, M., Wan, R., Armstrong, L. E., Schumacher, J. D., Rizzolo, D., Chow, M. D., Lee, Y. H., and Guo, G. L. (2018) FXR deletion in hepatocytes does not affect the severity of alcoholic liver disease in mice. Dig. Liver Dis. 50, 1068-1075

Zhang, Z., He, G., Han, G. S., Zhang, J., Catanzaro, N., Diaz, A., Wu, Z., Carman, G. M., Xie, L., and Wang, X. (2018) Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis. PLoS. Pathog. 14, e1006988

Zhong, F., Chen, H., Xie, Y., Azeloglu, E. U., Wei, C., Zhang, W., Li, Z., Chuang, P. Y., Jim, B., Li, H., Elmastour, F., Riyad, J. M., Weber, T., Chen, H., Wang, Y., Zhang, A., Jia, W., Lee, K., and He, J. C. (2018) Protein S Protects against Podocyte Injury in Diabetic Nephropathy. J. Am. Soc. Nephrol. 29, 1397-1410