Publications by RCLR members (2019)

Armstrong, L. E. and G. L. Guo 2019.  Understanding Environmental Contaminants' Direct Effects on Non-alcoholic Fatty Liver Disease Progression. Curr.Environ.Health Rep. 6, 95-104

Bankaitis, V. A. and G. M. Carman 2019.  The Role of Phosphoinositides in Signaling and Disease: Introduction to the Thematic Review Series. J.Lipid Res. 60, 227-228

Bott, A. J., J. Shen, C. Tonelli, L. Zhan, N. Sivaram, Y. P. Jiang, X. Yu, V. Bhatt, E. Chiles, H. Zhong, S. Maimouni, W. Dai, S. Velasquez, J. A. Pan, N. Muthalagu, J. Morton, T. G. Anthony, H. Feng, W. H. Lamers, D. J. Murphy, J. Y. Guo, J. Jin, H. C. Crawford, L. Zhang, E. White, R. Z. Lin, X. Su, D. A. Tuveson, and W. X. Zong 2019.  Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Rep. 29, 1287-1298

Brey, C. W., S. kbari-Alavijeh, J. Ling, J. Sheagley, B. Shaikh, F. Al-Mohanna, Y. Wang, R. Gaugler, and S. Hashmi 2019.  Salts and energy balance: A special role for dietary salts in metabolic syndrome. Clin.Nutr. 38, 1971-1985

Carman, G. M. and G. S. Han 2019.  Fat-regulating phosphatidic acid phosphatase: a review of its roles and regulation in lipid homeostasis. J.Lipid Res. 60, 2-6

Carman, G. M. 2019.  Discoveries of the phosphatidate phosphatase genes in yeast published in the Journal of Biological Chemistry. J.Biol.Chem. 294, 1681-1689

Castle, M., N. Fiedler, L. C. Pop, S. J. Schneider, Y. Schlussel, D. Sukumar, L. Hao, and S. A. Shapses 2019.  Three Doses of Vitamin D and Cognitive Outcomes in Older Women: A Double-Blind Randomized Controlled Trial. J.Gerontol.A Biol.Sci.Med.Sci. 5320009

Chen, D., W. Xu, Y. Wang, Y. Ye, Y. Wang, M. Yu, J. Gao, J. Wei, Y. Dong, H. Zhang, X. Fu, K. Ma, H. Wang, Z. Yang, J. Zhou, W. Cheng, S. Wang, J. Chen, B. D. Grant, C. L. Myers, A. Shi, and T. Xia 2019.  Revealing Functional Crosstalk between Distinct Bioprocesses through Reciprocal Functional Tests of Genetically Interacting Genes. Cell Rep. 29, 2646-2658

Dey, P., W. M. Su, M. Mirheydari, G. S. Han, and G. M. Carman 2019.  Protein kinase C mediates the phosphorylation of the Nem1-Spo7 protein phosphatase complex in yeast. J.Biol.Chem. 294, 15997-16009

Dong, B., A. B. Singh, G. L. Guo, M. Young, and J. Liu 2019.  Activation of FXR by obeticholic acid induces hepatic gene expression of SR-BI through a novel mechanism of transcriptional synergy with the nuclear receptor LXR. Int.J.Mol.Med. 43, 1927-1938

Foscolou, A., E. Critselis, S. Tyrovolas, C. Chrysohoou, L. S. Sidossis, N. Naumovski, A. L. Matalas, L. Rallidis, E. Polychronopoulos, J. L. yuso-Mateos, J. M. Haro, and D. Panagiotakos 2019.  The Effect of Exclusive Olive Oil Consumption on Successful Aging: A Combined Analysis of the ATTICA and MEDIS Epidemiological Studies. Foods. 8, foods8010025

Garretto, D., Y. K. Kim, L. Quadro, R. R. Rhodas, V. Pimentel, N. A. Crnosija, L. Nie, P. Bernstein, P. Tropper, and G. S. Neal-Perry 2019.  Vitamin A and beta-carotene in pregnant and breastfeeding post-bariatric women in an urban population. J.Perinat.Med. 47, 183-189

Green, A. L., A. Eid, L. Zhan, H. Zarbl, G. L. Guo, and J. R. Richardson 2019.  Epigenetic Regulation of the Ontogenic Expression of the Dopamine Transporter. Front Genet. 10:1099. doi: 10.3389/fgene.2019.01099. eCollection;%2019., 1099

Guo, J., H. Tao, A. Alasadi, Q. Huang, and S. Jin 2019.  Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice. Eat.Weight.Disord. 24, 91-96

Hassaninasab, A., L. S. Hsieh, W. M. Su, G. S. Han, and G. M. Carman 2019.  Yck1 casein kinase I regulates the activity and phosphorylation of Pah1 phosphatidate phosphatase from Saccharomyces cerevisiae. J.Biol.Chem. 294, 18256-18268

Hennessy, M., M. E. Granade, A. Hassaninasab, D. Wang, J. M. Kwiatek, G. S. Han, T. E. Harris, and G. M. Carman 2019.  Casein kinase II-mediated phosphorylation of lipin 1beta phosphatidate phosphatase at Ser-285 and Ser-287 regulates its interaction with 14-3-3beta protein. J.Biol.Chem. 294, 2365-2374

Jado, I., R. Escudero, B. Espigares, E. Lara, M. Rodriguez-Vargas, C. Garcia-Amil, B. Lobo, I. Rodriguez-Moreno, and A. Toledo 2019.  Rapid and Highly Sensitive DNA Flow Technology Platform to Detect Tick-Borne Bacterial Pathogens in Clinical Samples. Vector.Borne.Zoonotic.Dis. 10

Jonsson, W. O., N. S. Margolies, and T. G. Anthony 2019.  Dietary Sulfur Amino Acid Restriction and the Integrated Stress Response: Mechanistic Insights. Nutrients. 11, nu11061349

Kammire, D. E., M. P. Walkup, W. T. Ambrosius, L. Lenchik, S. A. Shapses, B. J. Nicklas, D. K. Houston, A. P. Marsh, W. J. Rejeski, and K. M. Beavers 2019.  Effect of Weight Change Following Intentional Weight Loss on Bone Health in Older Adults with Obesity. Obesity.(Silver.Spring). 27, 1839-1845

Konarzewska, P., Y. Wang, G. S. Han, K. J. Goh, Y. G. Gao, G. M. Carman, and C. Xue 2019.  Phosphatidylserine synthesis is essential for viability of the human fungal pathogen Cryptococcus neoformans. J.Biol.Chem. 294, 2329-2339

Kong, B., M. Zhang, M. Huang, D. Rizzolo, L. E. Armstrong, J. D. Schumacher, M. D. Chow, Y. H. Lee, and G. L. Guo 2019.  FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury. Dig.Liver Dis. 51, 570-576

Lelyveld, V. S., D. K. O'Flaherty, L. Zhou, E. C. Izgu, and J. W. Szostak 2019.  DNA polymerase activity on synthetic N3'-->P5' phosphoramidate DNA templates. Nucleic Acids Res. 47, 8941-8949

Lelyveld, V. S., D. K. O'Flaherty, L. Zhou, E. C. Izgu, and J. W. Szostak 2019.  DNA polymerase activity on synthetic N3'-->P5' phosphoramidate DNA templates. Nucleic Acids Res. 47, 8941-8949

Ma, X., N. K. Das, C. Castillo, A. Gourani, A. O. Perekatt, M. P. Verzi, and Y. M. Shah 2019.  SMAD family member 3 (SMAD3) and SMAD4 repress HIF2alpha-dependent iron-regulatory genes. J.Biol.Chem. 294, 3974-3986

Mamounis, K. J., N. R. Shvedov, N. Margolies, A. Yasrebi, and T. A. Roepke 2019.  The effects of dietary fatty acids in the physiological outcomes of maternal high-fat diet on offspring energy homeostasis in mice. J.Dev.Orig.Health Dis. 1-12

McCauliff, L. A., A. Langan, R. Li, O. Ilnytska, D. Bose, M. Waghalter, K. Lai, P. C. Kahn, and J. Storch 2019.  Intracellular cholesterol trafficking is dependent upon NPC2 interaction with lysobisphosphatidic acid. Elife. 8. pii: 50832. doi: 10.7554/eLife.50832., 50832

Moffett, S. X., E. A. Klein, G. Brannigan, and J. V. Martin 2019.  L-3,3',5-triiodothyronine and pregnenolone sulfate inhibit Torpedo nicotinic acetylcholine receptors. PLoS.One. 14, e0223272

Naumenko, D. J., M. Watford, S. S. Utami Atmoko, W. M. Erb, and E. R. Vogel 2019.  Evaluating Ketosis in Primate Field Studies: Validation of Urine Test Strips in Wild Bornean Orangutans (Pongo pygmaeus wurmbii). Folia Primatol.(Basel). %19:1-9. doi: 10.1159/000501933., 1-9

Neinast, M. D., C. Jang, S. Hui, D. S. Murashige, Q. Chu, R. J. Morscher, X. Li, L. Zhan, E. White, T. G. Anthony, J. D. Rabinowitz, and Z. Arany 2019.  Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Cell Metab. 29, 417-429

Nickels, J. T., Jr. 2019.  Anti-parasitic drug discovery takes a giant leap forward. J.Lipid Res. 60, 919-921

Nikonorova, I. A., Q. Zhu, C. C. Signore, E. T. Mirek, W. O. Jonsson, B. Kong, G. L. Guo, W. J. Belden, and T. G. Anthony 2019.  Age modulates liver responses to asparaginase-induced amino acid stress in mice. J.Biol.Chem. %20;294, 13864-13875

Nikonorova, I. A., Q. Zhu, C. C. Signore, E. T. Mirek, W. O. Jonsson, B. Kong, G. L. Guo, W. J. Belden, and T. G. Anthony 2019.  Age modulates liver responses to asparaginase-induced amino acid stress in mice. J.Biol.Chem. %20;294, 13864-13875

Nnah, I. C., B. Wang, C. Saqcena, G. F. Weber, E. M. Bonder, D. Bagley, C. R. De, G. Napolitano, D. L. Medina, A. Ballabio, and R. Dobrowolski 2019.  TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy. Autophagy. 15, 151-164

Park, J., Q. Zhu, E. Mirek, L. Na, H. Raduwan, T. G. Anthony, and W. J. Belden 2019.  BMAL1 associates with chromosome ends to control rhythms in TERRA and telomeric heterochromatin. PLoS.One. 14, e0223803

Pierce, M., D. Vengsarkar, J. E. McLaughlin, J. N. Kahn, and N. E. Tumer 2019.  Ribosome depurination by ricin leads to inhibition of endoplasmic reticulum stress-induced HAC1 mRNA splicing on the ribosome. J.Biol.Chem. 294, 17848-17862

Rivera-Nunez, Z., E. S. Barrett, E. A. Szamreta, S. A. Shapses, B. Qin, Y. Lin, H. Zarbl, B. Buckley, and E. V. Bandera 2019.  Urinary mycoestrogens and age and height at menarche in New Jersey girls. Environ.Health. 18, 24-0464

Rizzolo, D., K. Buckley, B. Kong, L. Zhan, J. Shen, M. Stofan, A. Brinker, M. Goedken, B. Buckley, and G. L. Guo 2019.  Bile Acid Homeostasis in a Cholesterol 7alpha-Hydroxylase and Sterol 27-Hydroxylase Double Knockout Mouse Model. Hepatology. 70, 389-402

Roepke, T. A., A. Yasrebi, A. Villalobos, E. A. Krumm, J. A. Yang, and K. J. Mamounis 2019.  The loss of ERE-dependent ERalpha signaling potentiates the effects of maternal high-fat diet on energy homeostasis in female offspring fed an obesogenic diet. J.Dev.Orig.Health Dis. 1-12

Russo, D. P., J. Strickland, A. L. Karmaus, W. Wang, S. Shende, T. Hartung, L. M. Aleksunes, and H. Zhu 2019.  Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across. Environ.Health Perspect. 127, 47001

Rutherford, J. C., Y. S. Bahn, B. B. van den, J. Heitman, and C. Xue 2019.  Nutrient and Stress Sensing in Pathogenic Yeasts. Front Microbiol. 10:442. doi: 10.3389/fmicb.2019.00442. eCollection;%2019., 442

Sampath, H. and R. S. Lloyd 2019.  Roles of OGG1 in transcriptional regulation and maintenance of metabolic homeostasis. DNA Repair (Amst). 81:102667. doi: 10.1016/j.dnarep.2019.102667. Epub;%2019 Jul 8., 102667

Schumacher, J. D. and G. L. Guo 2019.  Pharmacologic Modulation of Bile Acid-FXR-FGF15/FGF19 Pathway for the Treatment of Nonalcoholic Steatohepatitis. Handb.Exp.Pharmacol. 256:325-357. doi: 10.1007/164_2019_228., 325-357

Schumacher, J. D., B. Kong, J. Wu, D. Rizzolo, L. E. Armstrong, M. D. Chow, M. Goedken, Y. H. Lee, and G. L. Guo 2019.  Direct and Indirect Effects of Fibroblast Growth Factor (FGF) 15 and FGF19 on Liver Fibrosis Development. Hepatology. 10

Scialis, R. J., L. M. Aleksunes, I. L. Csanaky, C. D. Klaassen, and J. E. Manautou 2019.  Identification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its Metabolites. Drug Metab Dispos. 47, 1080-1092

Serrano-Saiz, E., M. C. Vogt, S. Levy, Y. Wang, K. K. Kaczmarczyk, X. Mei, G. Bai, A. Singson, B. D. Grant, and O. Hobert 2019.  SLC17A6/7/8 Vesicular Glutamate Transporter Homologs in Nematodes. Genetics. genetics

Sharma, P. and H. Sampath 2019.  Mitochondrial DNA Integrity: Role in Health and Disease. Cells. 8, cells8020100

Skop, N. B., S. Singh, H. Antikainen, C. Saqcena, F. Calderon, D. E. Rothbard, C. H. Cho, C. D. Gandhi, S. W. Levison, and R. Dobrowolski 2019.  Subacute Transplantation of Native and Genetically Engineered Neural Progenitors Seeded on Microsphere Scaffolds Promote Repair and Functional Recovery After Traumatic Brain Injury. ASN.Neuro. 11:1759091419830186. doi: 10.1177/1759091419830186., 1759091419830186

Stankeviciute, G., Z. Guan, H. Goldfine, and E. A. Klein 2019.  Caulobacter crescentus Adapts to Phosphate Starvation by Synthesizing Anionic Glycoglycerolipids and a Novel Glycosphingolipid. MBio. 10, mBio-19

Stankeviciute, G., A. V. Miguel, A. Radkov, S. Chou, K. C. Huang, and E. A. Klein 2019.  Differential modes of crosslinking establish spatially distinct regions of peptidoglycan in Caulobacter crescentus. Mol.Microbiol. 111, 995-1008

Szilagyi, J. T., L. Gorczyca, A. Brinker, B. Buckley, J. D. Laskin, and L. M. Aleksunes 2019.  Placental BCRP/ABCG2 Transporter Prevents Fetal Exposure to the Estrogenic Mycotoxin Zearalenone. Toxicol.Sci. 168, 394-404

Szilagyi, J. T., G. M. Composto-Wahler, L. B. Joseph, B. Wang, T. Rosen, J. D. Laskin, and L. M. Aleksunes 2019.  Anandamide down-regulates placental transporter expression through CB2 receptor-mediated inhibition of cAMP synthesis. Pharmacol.Res. 141:331-342. doi: 10.1016/j.phrs.2019.01.002. Epub;%2019 Jan 2., 331-342

Tambalis, K. D., D. B. Panagiotakos, G. Psarra, and L. S. Sidossis 2019.  Breakfast skipping in Greek schoolchildren connected to an unhealthy lifestyle profile. Results from the National Action for Children's Health program. Nutr.Diet. 76, 328-335

Ukey, R., T. Carmon, D. Hardman, N. Hill, and S. Fakas 2019.  The Yarrowia lipolytica PAH1 homolog contributes but is not required for triacylglycerol biosynthesis during growth on glucose. Yeast. 10

Vail, G. and T. A. Roepke 2019.  Membrane-initiated estrogen signaling via Gq-coupled GPCR in the central nervous system.  Steroids. 142:77-83. doi: 10.1016/j.steroids.2018.01.010. Epub;%2018 Jan 31., 77-83

Villa-Rodriguez, J. A., I. Ifie, G. A. Gonzalez-Aguilar, and D. E. Roopchand 2019.  The Gastrointestinal Tract as Prime Site for Cardiometabolic Protection by Dietary Polyphenols. Adv.Nutr. 10, 999-1011

Vincent, H., A. Amri, N. P. Castaneda-Alvarez, H. Dempewolf, E. Dulloo, L. Guarino, D. Hole, C. Mba, A. Toledo, and N. Maxted 2019.  Modeling of crop wild relative species identifies areas globally for in situ conservation. Commun.Biol. 2:136. doi: 10.1038/s42003-019-0372-z. eCollection;%2019., 136-0372

Wallace, T. C., R. L. Bailey, J. B. Blumberg, B. Burton-Freeman, C. O. Chen, K. M. Crowe-White, A. Drewnowski, S. Hooshmand, E. Johnson, R. Lewis, R. Murray, S. A. Shapses, and D. D. Wang 2019.  Fruits, vegetables, and health: A comprehensive narrative, umbrella review of the science and recommendations for enhanced public policy to improve intake. Crit Rev.Food Sci.Nutr. 1-38

Wang, H., Q. Zhang, G. Mao, O. Conroy, Y. Pyatski, M. J. Fevola, G. O. Cula, P. Maitra, R. Mendelsohn, and C. R. Flach 2019.  Novel confocal Raman microscopy method to investigate hydration mechanisms in human skin. Skin Res.Technol. 25, 653-661

Wang, X., Z. Sheng, L. Meng, C. Su, S. Trooskin, and S. A. Shapses 2019.  25-Hydroxyvitamin D and Vitamin D Binding Protein Levels in Patients With Primary Hyperparathyroidism Before and After Parathyroidectomy. Front Endocrinol.(Lausanne). 10:171. doi: 10.3389/fendo.2019.00171. eCollection;%2019., 171


Weaver, A. A., D. K. Houston, S. A. Shapses, M. F. Lyles, R. M. Henderson, D. P. Beavers, A. C. Baker, and K. M. Beavers 2019.  Effect of a hypocaloric, nutritionally complete, higher-protein meal plan on bone density and quality in older adults with obesity: a randomized trial. Am.J.Clin.Nutr. 109, 478-486

Wen, X., A. A. Baker, C. D. Klaassen, J. C. Corton, J. R. Richardson, and L. M. Aleksunes 2019.  Hepatic carboxylesterases are differentially regulated in PPARalpha-null mice treated with perfluorooctanoic acid. Toxicology. 416:15-22. doi: 10.1016/j.tox.2019.01.014. Epub;%2019 Jan 24., 15-22

Wisniewski, P. J., R. A. Dowden, and S. C. Campbell 2019.  Role of Dietary Lipids in Modulating Inflammation through the Gut Microbiota. Nutrients. 11, nu11010117

Xu, H., A. Diolintzi, and J. Storch 2019.  Fatty acid-binding proteins: functional understanding and diagnostic implications. Curr.Opin.Clin.Nutr.Metab Care. 22,  407-412

Xu, H., A. M. Gajda, Y. X. Zhou, C. Panetta, Z. Sifnakis, A. Fatima, G. C. Henderson, and J. Storch 2019.  Muscle metabolic reprogramming underlies the resistance of liver fatty acid-binding protein (LFABP)-null mice to high-fat feeding-induced decline in exercise capacity. J.Biol.Chem. 294, 15358-15372

Yimcharoen, M., S. Kittikunnathum, C. Suknikorn, W. Nak-On, P. Yeethong, T. G. Anthony, and P. Bunpo 2019.  Effects of ascorbic acid supplementation on oxidative stress markers in healthy women following a single bout of exercise. J.Int.Soc.Sports Nutr. 16, 2-0269

You, D., H. M. Shin, F. Mosaad, J. R. Richardson, and L. M. Aleksunes 2019.  Brain region-specific regulation of histone acetylation and efflux transporters in mice. J.Biochem.Mol.Toxicol. e22318

You, D., X. Wen, L. Gorczyca, A. Morris, J. R. Richardson, and L. M. Aleksunes 2019.  Increased MDR1 Transporter Expression in Human Brain Endothelial Cells Through Enhanced Histone Acetylation and Activation of Aryl Hydrocarbon Receptor Signaling. Mol.Neurobiol. 56, 6986-7002

Zhou, Y., X. P. Li, J. N. Kahn, J. E. McLaughlin, and N. E. Tumer 2019.  Leucine 232 and hydrophobic residues at the ribosomal P stalk binding site are critical for biological activity of ricin. Biosci.Rep. 39, BSR2019202